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Our publications

  • 2019

    • Device-detected Atrial Fibrillation. Mulder BA, van Gelder IC, Rienstra M. Circulation 2019 30880437
    • Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic MicroRNAs Among Extracellular Vesicles, HDL, and Ago-2. Florijn BW, Duijs JMGJ, Levels JH, Dallinga-Thie GM, Wang Y, Boing AN, Yuana Y, Stam W, Limpens RWAL, Au YW, Nieuwland R, Rabelink TJ, Reinders MEJ, van Zonneveld AJ, Bijkerk R Diabetes 2019 31506344         
    • Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis. Bijkerk R, Au YW, Stam W, Duijs JMGJ, Koudijs A, Lievers E, Rabelink TJ, van Zonneveld AJ. Front Pharmacol. 2019  30914951
    • Vascular Calcification and not Arrhythmia in Idiopathic Atrial Fibrillation Associates with Sex Differences in Diabetic Microvascular Injury miRNA Profiles. Dudink E, Florijn B, Weijs B, Duijs J, Luermans J, Peeters F, Schurgers L, Wildberger J, Schotten U, Bijkerk R, Crijns HJ, van Zonneveld AJ. Microrna. 2019 30465521
    • Protease-Activated Receptors Are Potential Regulators in the Development of Arterial Endofibrosis in High-Performance Athletes. Posthuma, Jelle J., Jens J. N. Posma, Goof Schep, Mart M. H. Bender, Rene van Oerle, Allard C. van der Wal, Hugo Ten Cate, and Henri M. H. Spronk. Journal of Vascular Surgery 2019 30314721
    • Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Posthuma, Jelle J., Jens J. N. Posma, Rene van Oerle, Peter Leenders, Rick H. van Gorp, Armand M. G. Jaminon, Nigel Mackman, Stefan Heitmeier, Leon J. Schurgers, Hugo Ten Cate, and Henri M. H. Spronk. Scientific Reports 2019. 30846818
    • Roles of Coagulation Proteases and PARs (Protease-Activated Receptors) in Mouse Models of Inflammatory Diseases. Posma, Jens J., Steven P. Grover, Yohei Hisada, A. Phillip Owens 3rd, Silvio Antoniak, Henri M. Spronk, and Nigel Mackman. Arteriosclerosis, Thrombosis, and Vascular Biology 2019 30580574
    • Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX. Visser, Mayken, René van Oerle, Hugo Ten Cate, Volker Laux, Nigel Mackman, Stefan Heitmeier, and Henri M. H. Spronk. Arteriosclerosis, Thrombosis, and Vascular Biology 2020. 31766871
    • Young-onset atrial fibrillation: Sex differences in clinical profile, progression rate and cardiovascular outcome. Marcos EG, De With RR, Mulder BA, Van Gelder IC, Rienstra M. Int J Cardiol Heart Vasc. 2019
    • Atrial fibrillation progression risk factors and associated cardiovascular outcome in well-phenotyped patients: data from the AF-RISK study. De With RR, Marcos EG, Dudink EAMP, Spronk HM, Crijns HJGM, Rienstra M, Van Gelder IC. Europace. 2019
    • Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset. Chua W, Easter CL, Guasch E, Sitch A, Casadei B, Crijns HJGM, Haase D, Hatem S, Kääb S, Mont L, Schotten U, Sinner MF, Hemming K, Deeks JJ, Kirchhof P, Fabritz L. BMC Cardiovasc Disord. 2019 31113362

  • 2018

    • Michiel Rienstra, Anne H. Hobbelt, Marco Alings, Jan G.P. Tijssen, Marcelle D. Smit, Johan Brügemann, Bastiaan Geelhoed, Robert G. Tieleman, Hans L. Hillege, Raymond Tukkie, Dirk J. Van Veldhuisen, Harry J. G. M. Crijns, and Isabelle C. Van Gelder. Targeted therapy of underlying conditions improves sinus rhythmmaintenance in patients with persistent atrial fibrillation: results of the RACE 3 trial. European Heart Journal (2018) 0, 1–10. doi:10.1093/eurheartj/ehx739 (PDF)
    • RR De With, EG Marcos, IC Van Gelder, M Rienstra. Atrial fibrillation progression and outcome in patients with young-onset atrial fibrillation. Europace. 2018 Mar6 DOI: 10.1093/europace/euy028. PubMed PMID: 29518195
    • Kotecha D, Breithardt G, Camm AJ, Lip GYH, Schotten U, Ahlsson A, Arnar D, Atar D, Auricchio A, Bax J, Benussi S, Blomstrom-Lundqvist C, Borggrefe M, Boriani G, Brandes A, Calkins H, Casadei B, Castellá M, Chua W, Crijns H, Dobrev  D, Fabritz L, Feuring M, Freedman B, Gerth A, Goette A, Guasch E, Haase D, Hatem  S, Haeusler KG, Heidbuchel H, Hendriks J, Hunter C, Kääb S, Kespohl S, Landmesser U, Lane DA, Lewalter T, Mont L, Nabauer M, Nielsen JC, Oeff M, Oldgren J, Oto A,  Pison L, Potpara T, Ravens U, Richard-Lordereau I, Rienstra M, Savelieva I, Schnabel R, Sinner MF, Sommer P, Themistoclakis S, Van Gelder IC, Vardas PE, Verma A, Wakili R, Weber E, Werring D, Willems S, Ziegler A, Hindricks G, Kirchhof P. Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference. Europace. 2018 Mar 1;20(3):395-407. doi: 10.1093/europace/eux318. PubMed PMID: 29300976
    • Michiel Rienstra, Anne H. Hobbelt, Marco Alings, Jan G.P. Tijssen, Marcelle D. Smit, Johan Brügemann, Bastiaan Geelhoed, Robert G. Tieleman, Hans L. Hillege, Raymond Tukkie, Dirk J. Van Veldhuisen, Harry J. G. M. Crijns, and Isabelle C. Van Gelder. Targeted therapy of underlying conditions improves sinus rhythm maintenance in patients with persistent atrial fibrillation: results of the RACE 3 trial. European Heart Journal. 2018 Feb 1. doi: 10.1093/eurheartj/ehx739. [Epub ahead of print]. PubMed PMID: 29401239
    • Spronk HMH, Padro T, Siland JE, Prochaska JH, Winters J, van der Wal AC, Posthuma JJ, Lowe G, d'Alessandro E, Wenzel P, Coenen DM, Reitsma PH, Ruf W, van  Gorp RH, Koenen RR, Vajen T, Alshaikh NA, Wolberg AS, Macrae FL, Asquith N, Heemskerk J, Heinzmann A, Moorlag M, Mackman N, van der Meijden P, Meijers JCM, Heestermans M, Renné T, Dólleman S, Chayouâ W, Ariëns RAS, Baaten CC, Nagy M, Kuliopulos A, Posma JJ, Harrison P, Vries MJ, Crijns HJGM, Dudink EAMP, Buller HR, Henskens YMC, Själander A, Zwaveling S, Erküner O, Eikelboom JW, Gulpen A, Peeters FECM, Douxfils J, Olie RH, Baglin T, Leader A, Schotten U, Scaf B, van Beusekom HMM, Mosnier LO, van der Vorm L, Declerck P, Visser M, Dippel DWJ, Strijbis VJ, Pertiwi K, Ten Cate-Hoek AJ, Ten Cate H. Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis. Thromb Haemost. 2018 Feb;118(2):229-250. doi: 10.1160/TH17-07-0492. Epub 2018 Jan 29. PubMed PMID: 29378352
    • Kotecha D, Chua WWL, Fabritz L, Hendriks J, Casadei B, Schotten U, Vardas P, Heidbuchel H, Dean V, Kirchhof P; European Society of Cardiology (ESC) Atrial Fibrillation Guidelines Taskforce, the CATCH ME consortium and the European Heart Rhythm Association (EHRA). European Society of Cardiology smartphone and tablet applications for patients with atrial fibrillation and their health care providers. Europace. 2018 Feb 1;20(2):225-233. doi: 10.1093/europace/eux299. PubMed PMID: 29040548
    • van Hunnik A, Nasrallah H, Lau DH, Kuiper M, Verheule S, Schotten U.  Vernakalant does not alter early repolarization or contractility in normal and electrically remodelled atria. Europace. 2018 Jan 1;20(1):140-148. doi: 10.1093/europace/eux025. PubMed PMID: 28449044
    • Ten Cate H, Olie RH, Ten Cate-Hoek AJ, Henskens YMC. Direct oral anticoagulants: When to consider laboratory testing? Int. J. Lab Hematol. 2018 May;40 Suppl 1:30-33. doi: 10.1111/ijlh.12816. PubMed PMID: 29741249
    • Mackman N, Spronk HMH, Stouffer GA, Ten Cate H. Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients. Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):726-732. doi: 10.1161/ATVBAHA.117.310048. Epub 2018 Feb 15. PubMed PMID: 29449336
    • Borst O, Münzer P, Alnaggar N, Geue S, Tegtmeyer R, Rath D, Droppa M, Seizer P, Heitmeier S, Heemskerk JWM, Jennings LK, Storey RF, Angiolillo DJ, Rocca B, Spronk H, Ten Cate H, Gawaz M, Geisler T. Inhibitory mechanisms of very low-dose rivaroxaban in non-ST-elevation myocardial infarction. Blood Adv. 2018 Mar 27;2(6):715-730. doi: 10.1182/bloodadvances.2017013573. PubMed PMID: 29588304

  • 2017

    • Kloosterman M, Rienstra M, Crijns HJ, Healey JS, Van Gelder IC. The left atrium: An overlooked prognostic tool. Eur J Prev Cardiol. 2017 Mar;24(4):389-391. doi: 10.1177/2047487316686633. Epub 2017 Jan 9. PubMed PMID: 28067538.
    • Linz D, Hohl M, Dhein S, Ruf S, Reil JC, Kabiri M, Wohlfart P, Verheule S, Böhm M, Sadowski T, Schotten U. Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats. Cardiovasc Res. 2016 Jun 1;110(3):371-80. doi: 10.1093/cvr/cvw071. Epub 2016 Mar 31. PubMed PMID: 27032673.
    • van Hunnik A, Nasrallah H, Lau DH, Kuiper M, Verheule S, Schotten U. Vernakalant does not alter early repolarization or contractility in normal and electrically remodelled atria. Europace. 2017 Apr 25. doi: 10.1093/europace/eux025. [Epub ahead of print] PubMed PMID: 28449044.
    • Hobbelt AH, Spronk HM, Crijns HJ, Ten Cate H, Rienstra M, Van Gelder IC. Prethrombotic State in Young Very Low-Risk Patients With Atrial Fibrillation. J Am Coll Cardiol. 2017 Apr 18;69(15):1990-1992. doi: 10.1016/j.jacc.2017.01.057. PubMed PMID: 28408030.
    • Van Gelder IC, Healey JS, Crijns HJ, Wang J, Hohnloser SH, Gold MR, Capucci A, Lau CP, Morillo CA, Hobbelt AH, Rienstra M, Connolly SJ. Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT. Eur Heart J. 2017 Mar 1. doi: 10.1093/eurheartj/ehx042. [Epub ahead of print] PubMed PMID: 28329139.
    • Van Gelder IC, Hobbelt AH, Brügemann J, Rienstra M. Time to implement fitness and reduction of fatness in atrial fibrillation therapy. Europace. 2017 Apr 1;19(4):513-514. doi: 10.1093/europace/euw287. PubMed PMID: 28431072.

  • 2016

    • Erküner Ö, Claessen R, Pisters R, Schulmer G, Ramaekers R, Sonneveld L, Dudink E, Lankveld T, Limantoro I, Weijs B, Pison L, Blaauw Y, de Vos CB, Crijns HJ. Poor anticoagulation relates to extended access times for cardioversion and is associated with long-term major cardiac and cerebrovascular events. Int J Cardiol. 2016 Dec 15;225:337-341. doi: 10.1016/j.ijcard.2016.10.018. Epub 2016 Oct 11. PubMed PMID: 27756038.
    • Posma JJ, Posthuma JJ, Spronk HM. Coagulation and non-coagulation effects of thrombin. J Thromb Haemost. 2016 Oct;14(10):1908-1916. doi: 10.1111/jth.13441. Epub 2016 Oct 5. Review. PubMed PMID: 27513692.
    • Spronk HM, De Jong AM, Verheule S, De Boer HC, Maass AH, Lau DH, Rienstra M, van Hunnik A, Kuiper M, Lumeij S, Zeemering S, Linz D, Kamphuisen PW, Ten Cate H, Crijns HJ, Van Gelder IC, van Zonneveld AJ, Schotten U. Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation. Eur Heart J. 2017 Jan 1;38(1):38-50. doi: 10.1093/eurheartj/ehw119. Epub 2016 Apr 12. PubMed PMID: 27071821. Schotten U, Dobrev D, Platonov PG, Kottkamp H, Hindricks G. Current controversies in determining the main mechanisms of atrial fibrillation. J Intern Med. 2016 May;279(5):428-38. doi: 10.1111/joim.12492. Epub 2016 Mar 16. Review. PubMed PMID: 26991914.
    • Gharaviri A, Verheule S, Eckstein J, Potse M, Kuklik P, Kuijpers NH, Schotten U. How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation. Europace. 2016 Feb 2. pii: euv445. [Epub ahead of print] PubMed PMID: 26838690.
    • Lankveld T, Zeemering S, Scherr D, Kuklik P, Hoffmann BA, Willems S, Pieske B, Haïssaguerre M, Jaïs P, Crijns HJ, Schotten U. Atrial Fibrillation Complexity Parameters Derived From Surface ECGs Predict Procedural Outcome and Long-Term Follow-Up of Stepwise Catheter Ablation for Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2016 Feb;9(2):e003354. doi: 10.1161/CIRCEP.115.003354. PubMed PMID: 26823480.
    • Opacic D, van Bragt KA, Nasrallah HM, Schotten U, Verheule S. Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation. Cardiovasc Res. 2016 Apr 1;109(4):527-41. doi: 10.1093/cvr/cvw007. Epub 2016 Jan 19. Review. PubMed PMID: 26786160.
    • Lankveld T, de Vos CB, Limantoro I, Zeemering S, Dudink E, Crijns HJ, Schotten U. Systematic analysis of ECG predictors of sinus rhythm maintenance after electrical cardioversion for persistent atrial fibrillation. Heart Rhythm. 2016 May;13(5):1020-7. doi: 10.1016/j.hrthm.2016.01.004. Epub 2016 Jan 8. PubMed PMID: 26776554.
    • Lau DH, Schotten U, Mahajan R, Antic NA, Hatem SN, Pathak RK, Hendriks JM, Kalman JM, Sanders P. Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications. Eur Heart J. 2016 May 21;37(20):1573-81. doi: 10.1093/eurheartj/ehv375. Epub 2015 Nov 17. Review. PubMed PMID: 26578197.
    • Van Gelder IC, Rienstra M, Crijns HJ, Olshansky B. Rate control in atrial fibrillation. Lancet. 2016 Aug 20;388(10046):818-28. doi: 10.1016/S0140-6736(16)31258-2. Review. PubMed PMID: 27560277.